Quality

Built into the process.Carried through every batch.

A pharmaceutical quality system supporting GMP manufacturing, testing and site batch release in Japan. Quality Assurance and Quality Control are involved from technology transfer through routine commercial supply.

Operator completing a checklist at a production line

Quality management systems

Clear requirements. Consistent execution.

Our quality system provides the framework for consistent manufacturing, testing, documentation and release of pharmaceutical products across the manufacturing lifecycle.

Quality Assurance

Batch documentation and release, deviation and CAPA management, change control, quality risk management and oversight of GMP operations.

Qualification & Validation

Equipment and facility qualification, process validation, cleaning validation and support for analytical method transfer and verification.

Materials & Suppliers

Incoming material controls, supplier qualification and management, sampling, testing and documentation.

Documentation & Training

Controlled GMP documentation, procedures, records and role-based training for consistent execution.

Chiharu Murakami
Our role is to establish clear quality requirements from the outset and ensure they are applied consistently throughout the manufacturing lifecycle.
Chiharu Murakami Head of Quality Assurance

Technology transfer & product introduction

Quality involvement starts with the transfer.

Together with the customer and our technical teams, QA and QC define and transfer the quality framework before commercial manufacturing begins.

  1. Stage 01

    Transfer

    Specifications, analytical methods, sampling requirements and acceptance criteria.

  2. Stage 02

    Validation

    Validation activities and product-specific controls.

  3. Stage 03

    Commercial supply

    An efficient transition into routine GMP supply.

  4. Stage 04

    Ongoing quality oversight

    Change control and continuing product support.

Quality control

In-house laboratory capabilities.

Testing in compliance with domestic and international regulations (PIC/S GMP, ICH): raw materials, in-process and finished products, plus selected testing for partner products. Analytical scope and methods are agreed for each program during transfer.

Testing services

Physicochemical testing

Compliant with JP, JPC, Japanese Standards of Quasi-drug Ingredients, JPE and JSFA.

Microbiological testing

Environmental monitoring, potency and microbial limits (non-sterile).

Stability testing

Long-term and accelerated studies based on PIC/S and ICH.

Laboratory equipment

HPLC with multiple detectorsUV-Vis spectrophotometerDissolution testerAutomatic titratorStability test chambers
Documentation check at production equipment

Customer quality interface

Customer audits are welcome at any stage.

Before and during an engagement. Responsibilities and interfaces are defined for each program in the applicable Quality Agreement.

Discuss your quality requirements
  • Product transfer and documentation
  • Deviations and investigations
  • Change control
  • Validation activities
  • Ongoing product support

Our teams work directly with your Quality organization on each of these.