Capabilities

Topical & semi-solid manufacturing

Creams, ointments, gels, lotions and other non-sterile topical formulations, made at our GMP site in Fujimino, Saitama. We support site transfers, new product introductions and portfolio consolidation for the Japanese market.

Emulsification

The scale your product needs.

Four vacuum emulsification vessels on two mixing technologies, Mizuho and Becomix, cover every production scale on one site.

60 L

Becomix

Development batches, technology transfer and scale-up studies.

250 L

Mizuho

Smaller commercial batches, specialty products and selected transfer or scale-up work.

650 L

Mizuho

Flexible mid-scale platform for established topical formulations.

1,200 L

Becomix

Large-scale commercial platform.

Temperature-controlled processingHigh-shear mixingVacuum deaeration

Equipment and batch suitability are assessed for each formulation and process.

Becomix vacuum emulsification vessels at the Fujimino site
Becomix vacuum emulsification
Mizuho vacuum emulsification vessel at the Fujimino site
Mizuho vacuum emulsification

Filling & packaging

From formulation to finished pack.

Equipment and process fit are assessed product by product: formulation, primary packaging, sealing, target output and downstream packaging needs.

Cartoning line at the Fujimino site

Resin & laminated tubes

Filling and hot-air sealing on our IWK platform.

Aluminum tubes

Filling and folding on our IWK and Suzuki Engineering platforms, for barrier-critical formulations.

Bottles & jars

Non-sterile liquids, lotions and large-volume topical presentations.

Downstream packaging

Cartoning, coding, labeling, checkweighing and protective wave-pack operations, integrated into the manufacturing flow.

Scope of support

Support throughout the product lifecycle.

  1. 01

    Technical feasibility

    Formulation, process, batch size, equipment fit, packaging, analytical methods, expected demand.

  2. 02

    Technology transfer

    Process mapping, critical parameters, material setup, documentation transfer, cross-functional risk review.

  3. 03

    Engineering & scale-up

    Engineering batches, process adaptation, filling and packaging trials, scale-dependent risk evaluation.

  4. 04

    Qualification & validation

    Qualification, process validation, cleaning validation, packaging validation and documentation per agreed scope.

  5. 05

    Quality control

    Method transfer or verification; raw material, in-process and finished-product testing within the agreed analytical scope.

  6. 06

    Commercial supply

    Material planning, routine GMP manufacturing, QC, batch-document review, release coordination, inventory and change control.

Starting a project

Start with technical feasibility.

For a new technology transfer, scale-up or portfolio consolidation, we begin with a confidential technical review.

A confidentiality agreement can be arranged before technical information is exchanged.

Typical information for an initial review

  • Dosage form
  • Target batch size and annual volume
  • Pack format
  • Current manufacturing process
  • Target transfer timing